README 967 B

123456789101112131415161718
  1. Bowtie is an ultrafast, memory-efficient short read aligner geared
  2. toward quickly aligning large sets of short DNA sequences (reads) to
  3. large genomes. It aligns 35-base-pair reads to the human genome at a
  4. rate of 25 million reads per hour on a typical workstation. Bowtie
  5. indexes the genome with a Burrows-Wheeler index to keep its memory
  6. footprint small: for the human genome, the index is typically about
  7. 2.2GB (for unpaired alignment) or 2.9GB (for paired-end or colorspace
  8. alignment). Multiple processors can be used simultaneously to achieve
  9. greater alignment speed. Bowtie can also output alignments in the
  10. standard SAM format, allowing Bowtie to interoperate with other tools
  11. supporting SAM, including the SAMtools consensus, SNP, and indel
  12. callers.
  13. If you use Bowtie for your published research, please cite:
  14. Langmead B, Trapnell C, Pop M, Salzberg SL.
  15. Ultrafast and memory-efficient alignment of short DNA sequences to
  16. the human genome. Genome Biol 10:R25.