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- Bowtie 2 is an ultrafast and memory-efficient tool for aligning
- sequencing reads to long reference sequences. It is particularly good
- at aligning reads of about 50 up to 100s or 1,000s of characters, and
- particularly good at aligning to relatively long (e.g. mammalian)
- genomes. Bowtie 2 indexes the genome with an FM Index to keep its
- memory footprint small: for the human genome, its memory footprint is
- typically around 3.2 GB. Bowtie 2 supports gapped, local, and paired-
- end alignment modes.
- Please cite:
- Langmead B, Salzberg S. Fast gapped-read alignment with Bowtie 2.
- Nature Methods. 2012, 9:357-359.
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