README 898 B

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  1. Cufflinks assembles transcripts, estimates their abundances, and tests
  2. for differential expression and regulation in RNA-Seq samples. It
  3. accepts aligned RNA-Seq reads and assembles the alignments into a
  4. parsimonious set of transcripts. Cufflinks then estimates the relative
  5. abundances of these transcripts based on how many reads support each
  6. one, taking into account biases in library preparation protocols.
  7. Cufflinks is a collaborative effort between the Laboratory for
  8. Mathematical and Computational Biology, led by Lior Pachter at UC
  9. Berkeley, Steven Salzberg's computational genomics group at the
  10. Institute of Genetic Medicine at Johns Hopkins University, and Barbara
  11. Wold's lab at Caltech.
  12. Reference:
  13. Ali Mortazavi, Brian A Williams, Kenneth McCue, Lorian Schaeffer and
  14. Barbara Wold, "Mapping and quantifying mammalian transcriptomes by
  15. RNA-Seq", Nature Methods, volume 5, 621 - 628 (2008)