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- TopHat is a fast splice junction mapper for RNA-Seq reads. It aligns
- RNA-Seq reads to mammalian-sized genomes using the ultra high-throughput
- short read aligner Bowtie, and then analyzes the mapping results to
- identify splice junctions between exons.
- TopHat is a collaborative effort between the Institute of Genetic
- Medicine at Johns Hopkins University, the Departments of Mathematics
- and Molecular and Cell Biology at the University of California,
- Berkeley and the Department of Stem Cell and Regenerative Biology at
- Harvard University.
- A recommended dependency is bowtie2.
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