README 1.3 KB

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  1. RepeatMasker is a program that screens DNA sequences for interspersed
  2. repeats and low complexity DNA sequences. The output of the program is a
  3. detailed annotation of the repeats that are present in the query
  4. sequence as well as a modified version of the query sequence in which
  5. all the annotated repeats have been masked (default: replaced by Ns).
  6. Currently over 56% of human genomic sequence is identified and masked by
  7. the program. Sequence comparisons in RepeatMasker are performed by one
  8. of several popular search engines including:
  9. - nhmmer (part of 'HMMER', available on SBo)
  10. - Cross_Match. Due to licensing, you should obtain this yourself:
  11. http://www.phrap.org
  12. - ABBlast/WUBlast. Due to licensing, you should obtain this yourself:
  13. https://blast.advbiocomp.com/licensing/
  14. - RMBlast (found as 'ncbi-rmblastn' on SBo)
  15. RepeatMasker makes use of curated libraries of repeats and currently
  16. supports Dfam (profile HMM library derived from Repbase sequences) and
  17. Repbase, a service of the Genetic Information Research Institute.
  18. WARNING!
  19. Due to the bundled databases, the installed size of this is 2.1 GB!
  20. NOTE!
  21. The package is installed in /opt. After install go fo /opt/RepeatMasker
  22. and run the RepeatMasker Configuration Program:
  23. # perl ./configure
  24. See README.SLACKWARE for details.